課程資訊
課程名稱
生理之輸送現象
TRANSPORT PHENOMENA IN PHYSIOLGICAL SYSTEMS 
開課學期
98-2 
授課對象
工學院  化學工程學研究所  
授課教師
蔡偉博 
課號
ChemE5009 
課程識別碼
524 U0470 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期一7,8,9(14:20~17:20) 
上課地點
化工三 
備註
與王勝仕合開
總人數上限:40人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/982transport 
課程簡介影片
 
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課程概述

1.Physical properties of the body fluids and the cell membrane
a.Body fluids and fluid compositions
b.Osmotic pressure and osmolarity
c.The cell membrane
d.Solute transport in biological systems

2.Elements of fluid mechanics: rheology of blood
a.Momentum, mass and energy balances
b.Fluid rheology
c.Dimensional analysis and scaling
d.The flow properties of blood

3.Fundamental of Mass Transport: Oxygen transport in biological systems
a.Introduction of diffusion concepts
b.Conservation mass
c.Convection/diffusion equation
d.Membrane transport
e.Oxygen transport

4.Pharmacokinetic analysis
a.Differential transport equation
i.Diffusion without reaction
ii.Diffusion with reaction
b.Entry routes for drugs
c.Factors that affect drug distribution
d.First-order drug absorption and elimination

5.Applications in extracorporeal devices
a.Membrane solute transport
b.Estimating the mass-transfer coefficients
c.Estimating the solute diffusivity in blood
d.Hemodialysis
e.Immobilized enzyme reactors

 

課程目標
Teach students transport of fluid and mass in the human body. The students will be expected to solve detailed biomedical related problems in fluid and mass transport. Topics to be covered include biological and artificial membranes, body fluids, the physical and flow properties of blood, tissue oxygen transport, pharmacokinetics, and applications in the extracorporeal devices and tissue engineering. 
課程要求
No requirement 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
以上課內容與講義為主 
參考書目
1.Basic transport phenomena in biomedical engineering / Ronald L. Rournier,
Edward Brothers, Lillington, NC, 1998.
2.Transport phenomena 2nd edition / Bird, Stewart and Lightfoot, John Wiley
& Sons Inc., 2
3. Biomedical Engineering Principles / D. O. Cooney, Marcel Dekker, 1976
4. Medical physiology / R. A. Rhoades and G. A. Tanner, Little, Brown and
Company, 1995.
5. Literature
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
期中考 
30% 
 
2. 
期末考 
30% 
 
3. 
作業 
15% 
 
4. 
期末報告(書面) 
15% 
 
5. 
期末報告(口頭) 
10% 
 
 
課程進度
週次
日期
單元主題
第1週
2/22  Introdcution_蔡偉博 
第2週
3/01  Cell membrane transport and interstitial fluid filtration_蔡偉博 
第3週
3/08  Cell membrane transport and interstitial fluid filtration_蔡偉博 
第4週
3/15  Solute Transport in Biological Systems_蔡偉博 
第5週
3/22  Solute Transport in Biological Systems_蔡偉博 
第6週
3/29  Solute Transport in Biological Systems_蔡偉博 
第7週
4/05  清明節 休假 
第8週
4/12  Pharmacokinetic Analysis_王勝仕 
第9週
4/19  Pharmacokinetic Analysis_王勝仕 
第10週
4/26  期中考 
第11週
5/03  The Physical and Flow Properties of Blood_蔡偉博 
第12週
5/10  Oxygen Transport in Biological Systems_蔡偉博 
第13週
5/17  Extracorporeal Devices_王勝仕 
第14週
5/24  Extracorporeal Devices_王勝仕 
第15週
5/31  Extracorporeal Devices_王勝仕 
第16週
6/07  期末報告 
第17週
6/14  期末報告